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Pharmaceutical Name (substance): Isotretinoin
Common Brand, Trade, Commercial Denominations: Roaccutane, Accutane, Isotretinoin, Amnesteem, Claravis, Decutan, Isotane, Sotret, Oratane, Izotek, Isotrex, Isotrexin, Accure, Aknenormin, Ciscutan, Clarus, Isohexal, Istretinoin-A, Isosupra, Isotroin, Atretin, Aberel, Airol, Aknefug, Aknoten, Dermairol, Eudyna, Lsotretinoin, Retisol-A, Solage, Stieva-A, Stieva-a Forte, Tri-Luma, Vitinoin.
Manufacturers: Roche, Taiji, Mylan, Barr, Actavis, Pacific Pharmaceuticals, Ranbaxy, Genepharm Australasia, BlauFarma, Stiefel, Alphapharm, Hermal, Pelpharma, Prepharm, Hexal Australia, Pharmathen, SMB, Cipla, Douglas Pharmaceuticals, Lafrancol.
Chemical IUPAC Name: (13cis)-retinoic acid
Molecular formula: C20 H28 O2
Molecular mass: 300.44 g/mol
Protein binding: 99.9%
Metabolism: Hepatic
Half life: 10–20 hours
Excretion: Renal and fecal
CAS number: 4759-48-2
Routes: Oral, topical
Drug category: Keratolytic Agents, Antineoplastic Agents, Cell Stimulants and Proliferants
Drug class: Retinoic acid isomer, vitamin A derivative
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