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Prozac (fluoxetine hydrochloride) is a prescription medication used for the treatment of depression, obsessive-compulsive disorder (OCD), bulimia, and panic disorder. It is one of a group of medications called selective serotonin reuptake inhibitors (SSRIs). As with all antidepressants, there may be an increased risk of suicidal behavior when taking Prozac.
A special warning is issued about the risk of suicidal thinking and behavior with antidepressant use in children and teenagers. The warning was issued in response to concerns that antidepressants seemed to increase the risk of suicidal behavior in children and teenagers in clinical studies.
In clinical studies, it did appear that there was a slightly increased risk of suicidal behavior in children and teenagers who took antidepressants, including Prozac. In one study, about 4 percent of children and teens taking an antidepressant had suicidal thoughts or behavior, compared to 2 percent in children and teens who were not taking an antidepressant. This study looked at all suicidal behavior, including suicides, attempted suicides, and thoughts about committing suicide. It is important to note that no one in the study actually committed suicide.
It is difficult to know for sure if antidepressants cause suicidal behavior. To make matters more confusing, depression itself can cause such behavior. The bottom line: You should report any signs of suicidal behavior to your healthcare professional, whether you are taking an antidepressant or not.
Certain people seem to be at higher risk for this behavior while taking antidepressants. This includes people with bipolar disorder (or a family history of bipolar disorder) and people who have attempted suicide (or who have a family history of suicide attempts).
What to watch for
Your healthcare provider should monitor you (or your child) carefully when first starting an antidepressant like Prozac. Be watchful for any signs of suicidal behavior. Contact your healthcare provider right away if you (or your child) have any of the following:
- Thoughts about death or committing suicide
- Suicide attempts
- Depression or anxiety that is new or worse
- Agitation, restlessness, or panic attacks
- Trouble sleeping (insomnia)
- Irritability that is new or worse
- Aggressive, angry, or violent behavior
- Acting on dangerous impulses
- Unusually increased talking or activity
- Other strange changes in mood or behavior.
Also, be sure to discuss the risks and benefits of using Prozac in children and teenagers. Your healthcare provider may be able to recommend other options for depression treatment.
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