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Testosterone Cypionate warnings and drug interactions

Testosterone Cypionate is used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty, impotence, or other hormonal imbalances. Testosterone Cypionate is also used in women to treat breast cancer that has spread to other parts of the body.

Testosterone Cypionate warnings

Androgen therapy with Testosterone Cypionate should be used cautiously in healthy males with delayed puberty. The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every 6 months. In children, androgen treatment may accelerate bone maturation without producing compensatory gain in linear growth. This adverse effect may result in compromised adult stature. The younger the child the greater the risk of compromising final mature height.

Testosterone Cypionate is contraindicated in males with carcinoma of the breast and carcinoma of the prostate gland and women who are or who may become pregnant and patients with hypersensitivity, serious cardiac, hepatic or renal disease.

Hypercalcemia may occur in immobilized patients. If this occurs, the drug should be discontinued. Prolonged use of high doses of androgens, like Testosterone Cypionate (principally the 17-a alkyl-androgens) has been associated with development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis – all potentially life-threatening complications.

Geriatric patients treated with androgens may be at increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking. Edema, with or without congestive heart failure, may be a serious complication in patients with pre-existing cardiac, renal or hepatic disease. Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism. This product contains benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal “Gasping Syndrome” in premature infants.

Drug interactions with Testosterone Cypionate

An interaction between medications does not always mean that you must stop taking one of them. The following medications may affect the way testosterone cypionate works, be affected by testosterone cypionate, or increase the risk of side effects:

* anti-diabetic drugs and insulin
* oxyphenbutazone
* warfarin

If you are taking any of these or other medications (including non-prescription, herbal, and supplement products), speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want to change your therapy or may suggest ways of managing any interactions. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your doctor know if you use them. Medications other than those listed above may also interact with this medication.

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