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Testosterone Suspension is used for treating symptoms of low testosterone in adult men when their bodies do not make any testosterone or not enough testosterone (hypogonadism). It may be used for other conditions as determined by your doctor. Testosterone is a male sex hormone. It works by replacing or supplementing the testosterone that is naturally made in the body.
Sexual dysfunction
Men with low testosterone levels commonly complain of decreased sex drive or erectile dysfunction. Treatment with Testosterone intramuscular injection is indicated for men with low total testosterone levels who have these symptoms. Regardless of the route of administration, studies have shown improvement in libido and sexual function in hypogonadal men. Other small, short-term trials of sexual function in men, including some with men who have normal testosterone levels, show mixed results. The optimal delivery method has not been determined.
Bone density, body composition, and muscle strength
The bone mineral density of hypogonadal men decreases as testosterone levels decrease, potentially increasing the risk of fractures. Bioavailable testosterone and estrogen levels are more correlated with density changes than total testosterone. Testosterone replacement may stop bone loss and increase bone density; however, many studies demonstrate equivocal results, and none have shown a decreased rate of fractures with testosterone therapy. Lean body mass increases consistently occur with testosterone treatment in healthy men; however, muscle strength does not significantly increase.
Depression, mood, cognition, and well-being
The indications for the use of testosterone in cognitive and psychological impairment are still unclear; however, studies of healthy older men with testosterone deficiency have yielded interesting results. Neuropsychological testing has revealed improvements in spatial cognition and spatial and verbal memory with testosterone replacement. No positive effects on mood or depression have been clearly demonstrated for hypogonadal men. Two trials (not placebo controlled) have demonstrated improvements in quality of life.
HIV and AIDS
Most men with human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) have decreased androgen levels, although the levels may remain in the low-normal range. Testosterone replacement has been shown to increase mood and sense of well-being in this population. Improvements in libido, energy, and muscle strength also have been demonstrated.
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