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The dose of sertraline hydrochloride (Zoloft) your healthcare provider prescribes will vary depending on a number of factors, including:
- Your age,
- The medical condition for which you are being treated,
- Other medical conditions you may have,
- Other medications you may be taking.
As is always the case, do not adjust your sertraline dose unless your healthcare provider specifically instructs you to do so.
Sertraline Dosage for Depression or Obsessive-Compulsive Disorder (OCD)
The recommended starting sertraline dose for people with depression or obsessive-compulsive disorder (OCD) is sertraline 50 mg once a day. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.
Sertraline Dosage for Panic Disorder, Post-traumatic Stress Disorder, or Social Anxiety Disorder
The recommended starting sertraline dose for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is sertraline 25 mg once a day. After a week, your healthcare provider will likely increase the dose up to 50 mg of sertraline once a day. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.
Sertraline Dosage for Premenstrual Dysphoric Disorder (PMDD)
The recommended starting dosage of sertraline for those with premenstrual dysphoric disorder (PMDD) is sertraline 50 mg once a day, throughout the entire menstrual cycle or just during the last two weeks of the cycle (before a woman's period starts), depending on the healthcare provider's instructions. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.
Sertraline Dosing and Children
The recommended starting dose of sertraline for children ages 6 to 12 with OCD is sertraline 25 mg once daily, while the starting dose of sertraline for adolescents ages 13 to 17 is sertraline 50 mg once daily. The child's healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if sertraline side effects occur.
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