Wartek - Wartec (podophyllotoxin)
Wartec Cream is a home application, indicated for the topical treatment of penile warts (condylomata acuminata), located in the preputial space, and for the treatment of external genital warts (condylomata acuminata) in women. The active ingredient in Wartec is podophyllotoxin 0.5%.
Podophyllotoxin is a plant extract that has antiwart properties. It works by destroying the skin of the wart.
Podophyllotoxin is a metaphase inhibitor in dividing cells binding to at least one binding site on tubulin. Binding prevents tubulin polymerisation required for microtubule assembly. At higher concentrations, podophyllotoxin also inhibits nucleoside transport through the cell membrane. The chemotherapeutic action of podophyllotoxin is assumed to be due to inhibition of growth and the ability to invade the tissue of the viral infected cells.
Wartec offers, together with two competing products (Aldera and Condyline/Condylox), the only treatment that is intended for self-administration by the patient.
Directions for use:
The affected area should be thoroughly washed with soap and water, and dried prior to application. Apply the solution, using only enough cream to just cover each wart, ensure that the solution is applied to the warts only and allow it to dry. Do not wash it off and do not exceed 0.5 ml per day. Apply Wartec twice daily, morning and evening, for 3 days only, followed by 4 days without treatment (one treatment course). If you have any warts remaining 7 days after you started using the solution, repeat the treatment course (twice a day for 3 days followed by 4 treatment-free days).
If you use it less often than you should, it may not resolve your warts. Using it more often than you should may not resolve your warts any faster. If you use Wartec for longer than your doctor tells you, the chance of side effects may increase. Generally a maximum of 4 treatment courses may be applied.
The majority of patients will not require in excess of 30 application loops for each application, however a maximum of 50 loops per application may be applied. Where lesions are greater than 4 cm², it is recommended that treatment takes place under the direct supervision of medical staff.
Wartec belongs to a group of genital warts medications.
Wartek Safety Info
Tell your doctor if you are using other creams, ointments or lotions or taking any other medicine. Your doctor may have more information on medicines to be careful with or avoid while using Wartec. Tell your doctor about any other medical conditions you have or have had.
Wartec helps most people with anogenital warts but it may have unwanted side effects in a few people. In most cases side effects are mild and will pass. They may occur on the second or third day of treatment as the warts begin to disappear. If you do not feel well or side effects persist, cause severe discomfort or they worry you, stop the treatment and tell your doctor.
The risk of systemic toxicity after topical apllication is increased by the treatment of large areas with excessive amounts for prolonged periods, by the treatment of friable, bleeding, or recently biopsied warts and by the inadvertent application to normal skin or mucous membranes. Podophyllotoxin is strongly irritant to the skin, eyes and mucous membranes and requires careful handling.
Do not use Wartec if you have an allergy to any of its ingredients or you are currently using other preparations containing podophyllotoxin. Do not use Wartec if you are pregnant or breastfeeding a baby - podophyllum can cause teratogenic effects and foetal death.
Immediately telephone your doctor, local hospital or Poisons Information Centre if you think that you, or anyone else may have swallowed Wartec Solution. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
- applied 2 times a day
- max 0.5 ml per day
Wartek Side Effects