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Xenical can be taken up to three times a day. The normal recommended daily dose for Xenical is one 120-mg capsule with meal that contains fat. Orlistat can be taken during meals or up to one hour after a meal. Take each dose with a full glass of water.
Each time you take Orlistat, your meal should contain no more than about 30% of calories from fat. If Orlistat is taken with any one meal that is very high in fat, there is an increased chance of digestive side effects.
Do not take more of this medication than has been prescribed for you. Doses greater than 120 mg three times a day have not been shown to provide an additional weight-loss benefit.
If a meal is missed or contains no fat, do not take a dose of Orlistat.
Orlistat may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of Orlistat.
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