Zyban is a nicotine-free quit-smoking aid. Instead of nicotine, it contains the chemical buproprion. It works by boosting the levels of several chemical messengers in the brain. With more of these chemicals at work, you experience a reduction in nicotine withdrawal symptoms and a weakening of the urge to smoke. More than a third of the people who take Zyban while participating in a support program are able to quit smoking for at least 1 month. Zyban can also prove helpful when people with conditions such as chronic bronchitis and emphysema decide it's time to quit.
Treatment with this drug begins while you are still smoking. Zyban needs about a week to reach an effective level in your body. So to improve your chance of success, you should not attempt to quit until the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban for 7 to 12 weeks.
This medicine works by boosting the level of chemicals in the brain (dopamine and norepinephrine). The result is that it can make you have a feeling of well being, it can energise you. This can help eliminate or lessen withdrawal from nicotine and it has been shown to be effective. Bupropion is approved for use in people who smoke 10 or more cigarettes a day and are at least 18 years old. It is used to help people when they quit smoking. Using bupropion for 7 to 9 weeks doubles the likelihood that you will still be tobacco-free 6 months after you quit. It works just as well as nicotine replacement therapies (NRTs).
Bupropion (under the brand name Wellbutrin) is aslo used to treat depression. Bupropion is also the active ingredient of Wellbutrin, an anti-depressant that is used for smoking cessation. However, bupropion's ability to help people quit smoking is not related to its antidepressant action. It can help you stop smoking even if you do not have depression. Bupropion is used to relieve symptoms of depression such as insomnia, sleeping too much, tiredness, changes in appetite, loss of interest in daily activities, worthlessness or guilt, feelings of sadness, and thoughts of death or suicide.
Directions for use:
The recommended and maximum dose of Zyban is 300 mg/day, given as 150 mg twice daily. Dosing should begin at 150 mg/day given every day for the first 3 days, followed by a dose increase for most patients to the recommended usual dose of 300 mg/day. There should be an interval of at least 8 hours between successive doses. Doses above 300 mg/day should not be used. Zyban should be swallowed whole and not crushed, divided, or chewed. Treatment with Zyban should be initiated while the patient is still smoking, since approximately 1 week of treatment is required to achieve steady-state blood levels of bupropion. Patients should set a “target quit date” within the first 2 weeks of treatment with Zyban, generally in the second week. Treatment with Zyban should be continued for 7 to 12 weeks. Longer treatment should be guided by the relative benefits and risks for individual patients.
Zyban belongs to a group of quit smoking medications.
Zyban Safety Info
Zyban should not be used by people with a history of eating disorders such as anorexia or bulimia, people already taking Wellbutrin, Wellbutrin SR or medications that contain buproprion hydrochloride, people who have taken or are taking monoamine oxidize inhibitors (MAOI) medication for depression, people with severe cirrhosis of the liver, people with a seizure disorder such as epilepsy. Bupropion hydrochloride can cause seizures in 1 in every 1000 people.
Zyban has not been tested in pregnant women. If you are pregnant or plan to become pregnant, do your best to quit smoking with the aid of counseling and support before turning to drug therapy. For the sake of the baby, you should avoid smoking or taking nicotine in any other form while pregnant.
There are many other drugs that can affect Zyban. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.
You can use nicotine patches along with Zyban. However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smoke while using a patch, because too much nicotine can cause serious side effects.
Zyban Side Effects
- dry mouth and